Our Location
304 North Cardinal St.
Dorchester Center, MA 02124
Glibenclamide Powder
Glibenclamide Powder is a white (to off-white) crystalline chemical raw material. Its molecular formula is C23H28ClN3O5S with a molecular weight of 494.00. It is commonly supplied in the form of Glibenclamide Powder for handling and formulation.
Product Name: Glibenclamide (Glyburide)
Appearance: White to off-white crystalline powder
Assay/Purity: ≥99% (HPLC)
CAS No.: 10238-21-8
Molecular Formula: C23H28ClN3O5S
Molecular Weight: 494.00
Quality System/Compliance: ISO / GMP / HACCP / USP
Manufacturing Capability: 1 factory, 3 production lines; GMP workshop; 2 independent laboratories
Packaging: 1 kg aluminum foil bag / 25 kg drum
Storage: Store in a cool, dry place, tightly sealed
MOQ: 1 kg
Genbay Biotechnology Co., Ltd. provides high-grade Glibenclamide Powder as a pharmaceutical-grade raw material for global supply, used for the management of type 2 diabetes mellitus. As a second-generation sulfonylurea, this compound is globally recognized for its potent ability to lower blood glucose levels by stimulating the release of insulin from pancreatic beta cells. Glibenclamide Powder functions by binding to specific receptors in the pancreas, closing ATP-sensitive potassium channels and facilitating the secretion of natural insulin. Our manufacturing process ensures a high-purity crystalline form with consistent particle size, making it an ideal active pharmaceutical ingredient (API) for the formulation of high-efficacy oral tablets and metabolic research studies.
Specification
The following data represents the typical profile for our Glibenclamide Powder.
- Assay: ≥99.0% (HPLC)
- Loss on Drying: ≤1.0%
- Residue on Ignition: ≤0.1%
- Heavy Metals: ≤10 ppm
- Melting Point: 172°C to 174°C
Uses
- Diabetes Management: The primary direct use of Glibenclamide Powder is as the active ingredient in medications designed to control high blood sugar in patients with type 2 diabetes.
- Insulin Secretion Research: Used in biochemical studies to investigate the mechanism of insulin release and the function of ATP-sensitive potassium channels.
- Metabolic Disease Studies: Utilized in laboratory settings to research the long-term effects of blood glucose regulation on cardiovascular and renal health.
- Pancreatic Function Analysis: Acts as a critical reference material for studying the physiological response of beta cells to sulfonylurea stimulation.
- Formulation Development: Highly suitable for the production of oral solid dosage forms (tablets) due to its stability and well-documented pharmacokinetic profile.
Quality Assurance & Certifications
Genbay produces Glibenclamide Powder in modern facilities that strictly adhere to international GMP and safety protocols.
- Testing Protocol: Every batch is subjected to rigorous analytical procedures, including HPLC for purity verification, dissolution testing, and full microbial screening.
- Certifications: Our production infrastructure is ISO and GMP certified, ensuring a reliable and consistent supply chain for pharmaceutical manufacturers worldwide.
- Documentation: We provide a comprehensive Certificate of Analysis (COA) and Material Safety Data Sheet (MSDS) with every shipment to ensure quality transparency.
Packaging & Shipping
- Packaging: 1 kg aluminum foil bags with vacuum sealing for moisture protection or 25 kg industrial-grade fiber drums for bulk production requirements.
- Shipping: We provide secure and tracked international shipping through professional chemical freight forwarders to ensure the material arrives safely.
- Storage: Glibenclamide Powder should be stored in a cool, dry place, protected from direct sunlight and kept tightly sealed to maintain its maximum shelf life.
Frequently Asked Questions(FAQ)
Q1: How does this material work to lower blood sugar?
A1: Glibenclamide Powder stimulates the pancreas to produce more insulin, which helps the body process dietary sugars more effectively.
Q2: Is the powder soluble in water?
A2: It is practically insoluble in water but shows good solubility in organic solvents like dimethylformamide (DMF) and is slightly soluble in ethanol.
Q3: What is the shelf life of the material?
A3: When stored under recommended conditions in a cool, dry environment, the shelf life is typically 36 months from the date of manufacture.
Q4: Do you provide batch-specific purity certificates?
A4: Yes, a detailed COA is issued for every single batch of Glibenclamide Powder to confirm its assay percentage and chemical profile.
Q5: What is the typical lead time for an international order?
A5: Standard orders are processed and dispatched within 3 to 5 business days, followed by worldwide delivery to your specified location.
Ready to request price, stock availability, or samples of Glibenclamide Powder?
Email: info@genbaybio.com
WhatsApp/Telegram: +852 94249370
Contact Genbay Biotechnology Co., Ltd.
